Approximately 25% of cancer patients suffer from cancer‐related fatigue (CRF) after cancer treatment. CRF is a multi‐factorial condition affected by several interrelated protective and perpetuating factors. As most studies merely assessed bivariate associations, more insight into the complex relationships among these constructs is needed. We applied the multivariate network approach to gain a better understanding of how patients’ fatigue, perpetuating and protective factors are dynamically interconnected.

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